All You Need To Know About Combiflam

1. What are Combiflam Tablets?

  • COMBIFLAM Tablets are a fixed dose combination (FDC) of two drugs – Ibuprofen (400 mg) and Paracetamol (325 mg) – two of the most commonly used analgesics worldwide.
  • Combiflam has the proven power of both these medicines in an optimum and safe dose in one Tablet.
  • It is currently amongst the most trusted painkiller brands in the country and is been selling in India for >35 years

2. What are common indications for consumption of Combiflam Tablets?

  • Headache
  • Toothache
  • Body ache
  • Fever
  • Muscular pain
  • Joint pain
  • Dysmenorrhea

3. What is the recommended dose for Combiflam tablets?

  • Adults: 1 tablet 3 times a day.
  • Adults and adolescents weighing from 40 kg body weight (aged 12 years and above): Initial dose, 1 tablet of Combiflam®. If necessary, additional doses of Combiflam® tablet can be taken.
  • The respective dosing interval should be chosen in line with the observed symptoms and the maximum recommended daily dose. It should not be below 6 hours. A total dose of 3 tablet of Combiflam® should not be exceeded in any 24-hour period.
  • For short-term use only.
  • If Combiflam® tablet is required in adults for more than 3 days in the case of fever or for more than 4 days for the treatment of pain or if the symptoms worsen the patient is advised to consult a physician.

4. What are the various products available under Combiflam?

Combiflam is available under 4 key brands namely:-

  • Combiflam Tablet (Ibuprofen 400 mg + Paracetamol 325 mg)
  • Combiflam Suspension (Ibuprofen 100 mg + Paracetamol 162.5 mg)
  • Combiflam ICYHOT – Gel & Spray (Diclofenac based topical pain reliever)
  • Combiflam Plus (Paracetamol 650 mg + Caffeine 50 mg)

5. What are the instructions for the use of Combiflam Tablets?

  • Tablets are to be taken by mouth with a glass of water, as directed by your doctor.
  • The tablets are to be taken with food or after food, but never on an empty stomach.
  • Never crush or chew the tablet

6. How does Combiflam work?

  • COMBIFLAM works by inhibiting the effects of cyclo-oxygenase (COX) enzymes. These enzymes are naturally present in our body and they aid in production of certain chemicals (known as prostaglandins) which are responsible for causing pain, swelling and redness at the site of injury.
  • Therefore, with inhibition of effects of COX enzymes; prostaglandin production is inhibited which in turn eases pain & inflammation, and increases the blood flow across the skin, heat loss and sweating.

7. Who should not take Combiflam?

  • People who are allergic to COMBIFLAM or any other constituent present in COMBIFLAM tablet
  • Who are Aspirin or any other Non-Steroidal Anti-Inflammatory Drug (NSAID) like Aspirin, Diclofenac, etc.
  • Who have a history of ulcer in stomach / intestine or if you have a history of bleeding in stomach.
  • Who have severe kidney or liver disease
  • Who have heart disease / heart failure / stroke
  • Who have from asthma or any other breathing problems
  • Who bleed easily
  • If a person had taken an earlier dose of COMBIFLAM or Aspirin or any other NSAID before and suffered from an attack of asthma, irritation of nose, swelling on face, itchy red bumps on skin or bleeding in stomach

8. Where can I buy Combiflam Tablet?

Combiflam tablet is available at most Chemist outlets in the country

9. Is COMBIFLAM addictive?

No it is not addictive.

10. Can I have COMBIFLAM with alcohol?

No. There is greater risk of liver damage in chronic alcoholics. Immediately inform your physician if you notice signs of bleeding in stomach (dried and coffee coloured blood in cough or stools).

11. Any particular food item to be avoided with COMBIFLAM?

No

12. Can I have COMBIFLAM when pregnant?

  • COMBIFLAM is not recommended for pregnant women.
  • Always inform your doctor if you are pregnant or plan to become pregnant.

13. Can I have COMBIFLAM when feeding a baby?

  • COMBIFLAM is not recommended for lactating women.
  • Always inform your doctor if you are breast-feeding your child.

14. Can I drive after taking Combiflam?

Yes there is no restriction but you should avoid driving if you feel dizzy, drowsy or sleepy after taking COMBIFLAM.

15. What happens if I overdose on Combiflam?

If you have taken an over-dose, it is advisable to contact your consulting physician immediately.

16. What happens if I have Combiflam with an expired date?

It is advisable to refrain from using an expired drug. But if you happen to eat one, it might not be as potent in treating your condition. However, It is very unlikely for a single dose of expired COMBIFLAM could produce an adverse event. Please do consult your physician if you feel unwell or sick after consuming an expired medicine.

17. What happens if I miss a dose of Combiflam?

It may not work well if you miss a dose because for effective working of the drug, a certain amount of drug must be present in your body at all times.

18. Can Combiflam cause a rash?

Like any other medicine it can cause a rash only if you are allergic to it. Allergy to pain killers is rare.

Myths Facts
Combiflam is sub-standard and should not be consumed

At Sanofi, our priority is safety of our patients, consumers and the communities we engage with. We ensure to follow the highest standard of safe and efficacious products globally. Combiflam tablet is approved by CDSCO, the highest drug regulatory body in India & been selling in India for the past >35 years.

Please refer to the link below for more clarity (can be used if needed)

Combiflam is banned in India Combiflam was never banned in India. It is widely available at Chemist stores and has been available in India for the past >35 years. Please do check with your doctor for more information or call our helpline on 1800-2222-95
Combiflam combination is banned globally Paracetamol and Ibuprofen are two most widely used pain killers globally and approved in many developed countries including USA, United Kingdom, Poland, New Zealand, Australia, and many others. Please consult your doctor for correct dosage instructions. Do call our helpline for more information on 1800-2222-95
Combiflam causes kidney damage For adults with no chronic diseases, Combiflam is safe and doesn’t cause kidney damage if taken in correct dose. Please consult your Doctor for correct dosage instructions.

Please feel free to call our helpline for more information on 1800-2222-95
Combiflam causes liver damage Combiflam tablet is a combination product of Paracetamol (325 mg) and Ibuprofen (400 mg). For adults with no chronic diseases, Combiflam is safe and doesn’t cause liver damage if taken in correct dose. Please consult your Doctor for correct dosage instructions.

Please feel free to call our helpline for more information on 1800-2222-95
Combiflam Contains steroids Combiflam contains no steroids. It is a pain relief solution which is a combination product of Paracetamol (325 mg) and Ibuprofen (400 mg) as its key ingredients. Ibuprofen is a Non-Steroidal Anti-inflammatory drug (NSAID) while Paracetamol is an anti-pyretic & analgesic. Both are very commonly used medications globally for the treatment of pain & fever.